J Natl Cancer Inst. 2011 May 17. Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow-up Study. (Harvard School of Public Health, Boston, MA)
- Prospective analysis of 47,911 men (Health Professionals Follow-up Study)
- Coffee >6 cups/day compared to no coffee
- Slightly lower risk for overall prostate cancer (425 vs 519/100k person-year)
- Substantially lower risk for lethal prostate cancer (34 vs 79/100k person-year)
- No difference with non-advanced/low-grade prostate cancer
- Regardless of decaf or caffeinated
- Possible links: insulin, testosterone, anti-oxidant, anti-inflammatory
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