- Previous finding: components of coffee extract inhibits viral multiplication.
- This article is about caffeic acid, which is
- another coffee components, unrelated to caffeine
- commonly found as chlorogenic acid
- esterification of quinic acid + caffeic acid
- a polyphenol, abundant in plants
- reported to have antioxidant activity
- Caffeic acid inhibits HSV-1 (virus causing cold sore) replication
- in vitro (HEp-2 cell culture)
- at early time point only
- However, neither chlorogenic acid nor quinic acid did show such antiviral activity.
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